The Roles of hnRNP Family in the Brain and Brain-Related Disorders

C Brandão-Teles, ASLM Antunes… - Molecular …, 2023 - Springer
… functions of hnRNPs in neurons, oligodendrocytes, microglia, … mRNA, including the hnRNP
F/H and A/B type hnRNP CBF-A… the myelin basic protein RNA trafficking sequence, and post-…

[PDF][PDF] Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons

N Fukuda, T Fukuda, P Percipalle, K Oda, N Takei… - Cell reports, 2023 - cell.com
hnRNP A/B (also called CArG-box binding factor A [CBF-A]) recognizes an 11-nucleotide
sequence that is similar to the RNA trafficking sequence (… of target mRNAs in oligodendrocytes, …

[HTML][HTML] Comprehensive atlas of the myelin basic protein interaction landscape

EV Smirnova, TV Rakitina, RH Ziganshin, GP Arapidi… - Biomolecules, 2021 - mdpi.com
… It preferentially binds long clusters of UG-rich sequences in … hnRNP A2 protein level in the
cytoplasm of oligodendrocyteshnRNP K, E1, F, and CBF-A in the complex with MBP mRNA

A dynamic actin-dependent nucleoskeleton and cell identity

T Venit, NH El Said, SR Mahmood… - The journal of …, 2021 - academic.oup.com
… immunoprecipitations combined with deep sequencing (ChIP-seq) … the A/B-type hnRNP
CBF-A/hnrnpab and accompanies RNA … by the actin-hnRNP U/SAF-A complex binding to the …

Prenatal stress induces translational disruption associated with myelination deficits

GK Crombie, HK Palliser, JC Shaw, BA Hanley… - Dev. Neurosci, 2023 - karger.com
… a surge of OL differentiation is accompanied by an increase in … OLIG2 mRNA expression (a
marker of total oligodendrocyte … to colocalize with MBP mRNA and hnRNP A2 in granules that …

[PDF][PDF] Cellular hnRNPAB binding to viral nucleoprotein inhibits flu virus replication by blocking nuclear export of viral mRNA

X Wang, L Lin, Y Zhong, M Feng, T Yu, Y Yan, J Zhou… - Iscience, 2021 - cell.com
… nuclear ribonucleoproteins (hnRNPs) play critical roles in the … viral mRNA nuclear export via
inhibiting viral mRNA binding … RNA packing, nuclear trafficking, and vRNA transcription and …

[HTML][HTML] MicroRNAs dysregulated in multiple sclerosis affect the differentiation of CG-4 cells, an oligodendrocyte progenitor cell line

O Perdaens, P Bottemanne… - Frontiers in Cellular …, 2024 - frontiersin.org
… potential mRNA targets by crossing the data of in silico analysis and RNA sequencing, …
We hypothesized that miR-214-3p targets Errfi1 and growth factor receptor bound protein 2 (…

[HTML][HTML] Contribution of RNA/DNA binding protein dysfunction in oligodendrocytes in the pathogenesis of the amyotrophic lateral sclerosis/frontotemporal lobar …

CF Valori, M Neumann - Frontiers in neuroscience, 2021 - frontiersin.org
binding to several transcripts (1a) and regulating pre-mRNA … RNA sequencing studies that
revealed that only some human … In cultured oligodendrocytes, oxidative insult induces stress …

[HTML][HTML] Research Progress on the Structural and Functional Roles of hnRNPs in Muscle Development

Z Li, H Wei, D Hu, X Li, Y Guo, X Ding, H Guo, L Zhang - Biomolecules, 2023 - mdpi.com
… of the U2AF heterodimer complex by binding to the polypyrimidine sequence of pre-mRNA. …
[107], it was discovered that hnRNP D binds to the ARE sequence of pre-mRNA and …

Hnrnpab regulates neural cell motility through transcription of Eps8

AA Lampasona, K Czaplinski - Rna, 2019 - rnajournal.cshlp.org
linked to the cytoplasmic localization or trafficking of mRNAs, … Hnrnpab sequence that has
been found among these ODN … It is interesting to note that the Hnrnpab paralog, AUF1/hnRNP